It looks like a crazy quilt spread over the continent. But a new map of emergency stroke care in America shows just how much of a patchwork system we still have for delivering the most effective stroke treatment.
Only 4.2 percent of more than 844,000 stroke victims received the drug called tPA, or another urgent stroke treatment, the study finds. If given in the first hours after a stroke, tPA and other treatments can restore blood flow in the brain and prevent the damage that causes stroke-related disability and drives up the long-term cost of caring for stroke survivors. But when the researchers looked at how tPA was used – or not – in Medicare participants who had strokes in each of the nation’s 3,436 different hospital markets between 2007 and 2010, deep divides emerged. In one-fifth of these regions, no patients receive tPA.
Meanwhile, in places like Stanford, CA and Asheville, NC, as many as 14 percent of stroke patients received tPA through an intravenous line, or a direct-to-brain (intrarterial) treatment that involved tPA or another strategy.
Even after they adjusted for the number of strokes that each region reported during the four years, there was a wide gap in use of emergency stroke treatment. In addition, older patients, women, and members of racial and ethnic minority groups were less likely to receive tPA no matter where they lived.
And while patients were somewhat more likely to get tPA if they had their strokes in regions where hospitals were certified as primary stroke centers, which can deliver tPA around the clock, or where ambulance companies had a policy of driving stroke patients further to get to a stroke center, those factors didn’t make a major difference.
“We can clearly do much better, but existing policy solutions are only going to get us so far,” says Burke. “In our findings, we do see positive results from primary stroke center designation and ambulance bypass, but we are talking about a complex mix of hospital, EMS, and individual response to stroke. We need to understand better what the areas with the highest rates of use are doing differently.”
At the time of the study’s data, comprehensive stroke center designation, which indicates the most advanced level of stroke care including intrarterial tPA, was not yet in use. The researchers calculated that if all regions achieved the same rates of tPA use as the Stanford region, more than 92,800 people would get treated, and 8,078 people would survive their stroke disability-free. Even if all regions doubled their current tPA use, 7,206 people would be spared disability. Variation in tPA use did track to lower average levels of education and income, and higher unemployment, in hospital service areas, and use was slightly higher across all densely populated areas compared with more sparsely populated areas. But the top 20 areas for tPA use are scattered across the country, in urban and rural areas, rich and poor ones.
The study was funded by the National Institute for Neurological Disorders and Stroke, and by the National Institute of Minority Health and Health Disparities. NS073685, MD008879, NS082597.
In addition to Burke and Skolarus, the authors are William J. Meurer, MD, MS; Krithika Shanmugasundaram, BS; Eric E. Adelman, MD; and Phillip A. Scott, MD. All are members of the U-M Health System’s Comprehensive Stroke Program, and all except Shanmugasundaram are members of the U-M Institute for Healthcare Policy and Innovation.
- Reference: Stroke, July 2015, doi: 10.1161/STROKEAHA.115.009163
- Source: Kara Gavin – U-M Health System